Friday, 11 July 2014

Custom Antibody Services...


Custom Antibody Services...
 
Unique Advantages of ProSci

Flexible service packages at competitive prices

In-house labs and animal facilities in San Diego, (USA)

Confidentiality of your work is important to us

You retain the rights to any products from our services

Capable of supporting large or small projects

Custom Antibody Packages Available

Polyclonal Custom Antibody Production Services

Monoclonal Custom Antibody Production Services

Additional Custom Antibody Services
ProSci offers custom polyclonal and monoclonal antibody production services using its own in-house labs and animal facilities (USDA licensed and NIH/OLAW approved) in San Diego, California.
  • Complimentary antigen design and peptide synthesis
  • ChIP grade custom antibodies produced
  • Well published custom antibodies
  • Rabbits bred in-house - large bred rabbits for larger bleeds
  • Dedicated technician on site 24/7 with over 20 years of experience
  • Extensive range of custom antibody services
  • Flexible service packages at competitive prices
  • In house laboratories and animal facilities in San Diego, California
  • All services performed in confidence

Summary of Custom Polyclonal Antibody Services
ProSci produces polyclonal antibodies in rabbits, mice, rats, guinea pigs, chickens, goats, or llamas.
Item
Serum package
Peptide Package
Purified Package
Anti-Sera Schedule
Peptide Synthesis

Peptide Conjugation

ELISA Report

Affinity Purification



Summary of Custom Monoclonal Antibody Services
Detailed information regarding the different custom monoclonal antibody packages available are detailed on the ProSci website, and the following links will take you through to these pages.


Additional Custom Antibody Services
To complement their polyclonal and monoclonal antibody production services, ProSci Incorporated offers the following custom services:
Caltag Medsystems are the exclusive distributor of ProSci Products in the UK and Ireland. To order; simply call, fax or email using the following contact details:
Tel: +44 (0) 1280 827460 or 0800 279 9113
Fax: +44 (0) 1280 827466 or 0800 279 9114
Email: office@caltagmedsystems.co.uk
Address: Whiteleaf Business Centre, 11 Little Balmer, Buckingham, MK18 1TF, UK.
www.caltagmedsystems.co.uk 
<http://www.caltagmedsystems.co.uk> 
Caltag Medsystems have
been accredited to
ISO13485:2003 standard.
facebook
twitter
linkedin
blogger

You have received this message because you are a customer of Caltag Medsystems or you have previously expressed an interest in our products and services. If you do not wish to receive further newsletters from Caltag Medsystems, please simply unsubscribe here and your details will be removed from our newsletter database immediately. If you would prefer mailings to be sent to another address, please subscribe using the new address here: www.caltagmedsystems.co.uk or contact us at: office@caltagmedsystems.co.uk.

Caltag MedSystems is a limited company registered in England and Wales.
Registered office: Whiteleaf Business Centre,
11, Little Balmer, Buckingham, MK18 1TF, UK
Registered number: 4162330
VAT Number: GB 765 66 6189


Please note that Caltag Medsystems may monitor email traffic data and also the content of email for the purposes of security and staff training.


This message contains confidential information and is intended only for the intended recipients. If you are not an intended recipient you should not disseminate, distribute or copy this e-mail. Please notify caltagmedsystems@caltagmedsystems.co.uk immediately by e-mail if you have received this e-mail by mistake and delete this e-mail from your system. E-mail transmission cannot be guaranteed to be secure or error-free as information could be intercepted, corrupted, lost, destroyed, arrive late or incomplete, or contain viruses. Caltag Medsystems therefore does not accept liability for any errors or omissions in the contents of this message, which arise as a result of e-mail transmission. If verification is required please request a hard-copy version.

Thursday, 10 July 2014

Infectious Disease Antibodies

Infectious Diseases are illnesses caused by viruses, bacteria, fungi, protozoa, and parasites. Some examples of illnesses stemming from these agents are respiratory, gastrointestinal, and sexually transmitted diseases. Each type of disease offers different avenues of infection and different approaches to its control.

A sampling of ProSci Infectious Disease Antibodies and Antigens:

Tropical Diseases:
Diseases prevalent in or unique to a tropical region known as Tropical Diseases. These diseases usually are transmitted via insect “bite” from a variety of sources with mosquitoes and flies as the most common vector. As vaccines are not readily available for most tropical diseases, ProSci is proud to offer a diverse catalog of tropical disease antibodies such as West Nile Virus, Borrelia burgdorferi, Dengue Virus, and Marburg Virus.

TORCH:
Vertically transmitted infections can be caused by bacteria and viruses. Several vertically transmitted infections can be linked to the Torch complex:
O: Other infections ***

*** Also included are the pathogens syphilis, hepatitis B, Coxsackie virus, Epstein–Barr virus (EBV), human parvovirus, and varicella zoster (VZV).

These diseases can cause congenital infections leading to significant birth defects and even fetal death.

Sexually Transmitted Diseases:
Sexually Transmitted  Diseases (STDs) are transmitted usually through sexual contact. The causes of sexually transmitted diseases are bacterial, parasitic, and viral. According to the World Health Organization more than 1 million people acquire a sexually transmitted infection every day. ProSci presents an excellent range of STD antibodies, including targets such as Chlamydia, Hepatitis B, Hepatitis C, Herpes Simplex Virus, HIV 1, Human Papilloma Virus, Neisseria gonorrhoeae, and Treponema pallidum.

Respiratory Infections:
Respiratory tract infections range in severity from relatively mild infections, such as the common cold, to potentially life-threatening infections, including pneumonia. Reported outbreaks are usually associated with general exposure within contained places such as cruise ships and hotels. Viral pathogens are the most common cause of respiratory infection. Common vial antibodies ProSci offers in our catalog include rhinovirus, influenza virus, Parainfluenza virus, coronavirus (SARS), adenovirus, and respiratory syncytial virus. Bacterial pathogens are less common but nonetheless, still cause a threat. Common vial antibodies ProSci offers in our catalog include Streptococcus pneumoniae, Mycoplasma pneumoniae, and Legionella pneumophila.

Food and Water Safety:
Foodborne illnesses are the direct result of ingestion of substances contaminated with microorganisms or chemicals. These diseases are common, yet most are preventable. Caused by a variety of viruses, bacteria, parasites, toxins, metals, and prions, more than 250 foodborne diseases have been described. Even with the aid of modern technology, it is still hard to determine the specific microorganisms responsible for foodborne illness outbreaks.

ProSci carries antibodies to the following antigens in relation to foodborne illnesses:


Toxins and Biological Material:
Biological (Germ) warfare is the intentional use of disease causing organisms and/or toxins to injure, kill, and/or weaken enemy's resistance to attack and reduce the will to wage war. Often referred to as “the poor man’s nuclear bomb” are cheap and easy to produce, and can decimate entire populations.  These biological agents can be classified as Bacteria, Viruses, Rickettsiae, Chlamydia, Fungi, and Toxins. Since the Sept 2001 attacks within the USA some of the most commonly researched are Anthrax and various Viral Hemorrhagic Fevers (like Hantavirus (Hantaan), Rift Valley Fever Virus, and Marburg Virus).

For a complete listing of ProSci’s infectious Disease antibodies, click here.

ProSci products are exclusively distributed in the UK and Ireland by Caltag Medsystems. for further information about ProSci products please email office@caltagmedsystems.co.uk or call 01280 827460.

Melanocyte Pigmentation

Melanocytes are neural crest-derived cells that are found primarily in the basal layer of the epidermis.


Melanocyte progenitors are known as melanoblasts. These cells are proliferative, express little melanin, and frequently display a bi-polar phenotype with two dendrites.


In response to differentiation signals, melanoblasts form membrane bound vesicles known as melanosomes in which melanin granules form, and increase dendricity. To complete pigmentation of the epidermis, melanosomes (and their melanin granules) are transferred to neighbouring keratinocytes via the dendrites.

In vitro melanocyte pigmentation is commonly investigated by quantifying either:
With powerful growth factors, it has been possible to develop media that deliver good growth and features of differentiation such as increased dendricity and melanin expression.
Caltag Medsytems can provide you with this unique media, and are also able to supply the melanocyte cells.

- Melanocyte Medium (product code: CnT-40), 500 ml
- Melanocyte Medium, Free Sample (product code: CnT-AG2-SAMPLE), 250 ml.

To request your free of charge sample, please send your order to office@caltagmedsystems.co.uk, or fax to 01280 827466. Please note that there will be a £25.50 shipping and dry ice charge which will be needed to be included on your order.

- Epidermal Melanocytes, Adult, Single donor (product code: HEMas)
- Epidermal Melanocytes, Juvenile, Single donor (product code: HEMns)

Caltag Medsystems is the UK distributor of CellnTec products. For further information about CellnTec please click here

Tuesday, 8 July 2014

Angiogenesis Image Analysis


Angiogenesis Image Analysis  
Quantify your In Vitro Angiogenesis Assays using Cellworks Image Analysis Software or Services
  


The AngioSys 2.0 image analysis software provides a semi-automated analysis of angiogenesis by measuring tubule area, length and number of tubule junctions





Ideal for customers preferring the in-house specialists at Cellworks to analyse images.  Customer reports detail the tubule length, number of junctions, frequency and mean number of branches for each image
AngioSys 2.0 Image Analysis Software
'The AngioSys 2.0 image analysis software provides a semi-automated analysis of angiogenesis by measuring tubule area, length and number of tubule junctions.’
Angiosys 2.0 is custom built software developed to quantitate tubules formed during in vitro angiogenesis assays based on the co-culture of endothelial cells with fibroblasts.  
The software is regularly used to quantitate images of angiogenesis tubules obtained from conducting the Cellworks Angiogenesis Assay Kit: V2a kit Vasculogenesis to Angiogenesis (Product Code ZHA-4000), which uses the anti-CD31 based staining kit (ZHA-1225). 
Image files can be conveniently grouped and processed to provide quantitative & repeatable measurements of tubule areas, lengths and number of junctions. Repetitive image processing sequences can be specified, saved and applied to groups of images to enable rapid analysis. The resulting data can be exported as a csv file in spreadsheet format.
Benefits
  • Measures number of junctions, number of tubules, total tubule length and mean tubule length
  • Operates on Windows XP, Vista, Windows 7, Windows 8, 32 bit, 64 bit
  • Able to analyse TIFF, BMP, GIF, JPEG, PNG images
  • 21 day trial available
  • Available as an internet download – quick and easy
AngioSys 2.0 software is available in two formats: 
  • A 21 day demonstration version, product code ZHA-5000D. Downloaded free of charge
  • Full licence, product code ZHA-5000, £350/€455/$613. Activation of the full licence requires a serial key number which will be emailed upon receipt of a purchase order.  
Angiogenesis Image Analysis Service
‘Ideal for customers preferring the in-house specialists at Cellworks to analyse their images. Customer reports detail the tubule length, number of junctions, frequency and mean number of branches for each image’
  • Ideal when analysis is required on only a small number of images
  • Suitable for analysis of large numbers of angiogenesis assay images – when manpower in the lab is short
  • Perfect for customers new to angiogenesis image analysis 
Product Code
Product Description
List Price £
List Price €
List Price $
Angiogenesis Image Analysis Service - First 24 Images
£20 per image
€36 per image
$35 per image
Angiogenesis Image Analysis Service - Additional Images
£10 per image
€13 per image
$17.50 per image
Image Analysis Service Set Up Charge
£50 one off payment
€65 one off payment
$87.50 one off payment
Reports are sent by email as a .csv file. If conversion to SI units is preferable a calibration image taken using the same magnification and adaptor settings is required. 
Report Example
Pricing is charged per image analysed. Please note that there is a one off set up charge payment required, product code: ZHA-6002
For further information regarding Cellworks products please click here.

Where do you read the latest journals?
Here at Cellworks we would love to know which publications you read and a little bit about your research too. It helps ensure we are developing products that our customers have highlighted as being important to them. Below is a link to a short survey that we would gratefully appreciate your feedback in. As a thank you for helping us out, we are offering 5x £50/$85/€60 amazon vouchers to the five customers supplying the most helpful sets of answers. 
Cellworks is a division of Caltag Medsystems dedicated to the manufacture of angiogenesis reagents. To order; simply call, fax or email using the following contact details:
Tel: +44 (0) 1280 827460 or 0800 279 9113
Fax: +44 (0) 1280 827466 or 0800 279 9114
Email:
cellworks@caltagmedsystems.co.uk
Address: Whiteleaf Business Centre, 11 Little Balmer, Buckingham, MK18 1TF, UK.
www.cellworks.co.uk 
<http://www.cellworks.co.uk> 
Caltag Medsystems have
been accredited to
ISO13485:2003 standard.
facebook
twitter
linkedin
blogger



Friday, 27 June 2014

Welcome to BrainBits: Your Catalyst for New Discoveries.

BrainBits® narrows the gap between research and discovery by providing fresh, never frozen, micro-surgically dissected, animal brain tissues. And you’ll get what you need fast! BrainBits® ships tissue right to your door overnight: Your research begins immediately.

Key Benefits:

- Fresh Tissue
- More Viable Cells
- No need to deal with live animals
- Entrust tissue management to a skilled specialist
Fresh is more: More cells. More research. More discovery. This is why major pharmaceutical companies, biotechnology firms, and universities around the world use and reference BrainBits® in their published discoveries. Now, you can too.

In addition to increased convenience, BrainBits® fresh tissue delivers more viable cells than frozen offerings. Your tissue is never exposed to stressful freezing or thawing cycles. This means greater opportunity for discovery, without lead times, without thawing, and without delay. BrainBits® puts what you are searching for within reach, faster and more reliably than you may have thought possible.

You no longer need to write and manage protocols or experience the headaches of dealing with live animals. The experts at BrainBits® assure consistent, uniform, and reliable dissection so you will never have to jump through hoops for your raw materials. Just place your tissue order with BrainBits® and your research can begin as soon as your tissue arrives at your door.

Like so many worthwhile and challenging endeavours, in the race for discovery, protocols are precise and consistency is key. Meticulous tasks like harvesting neuronal tissue are vital to your research yet add unnecessary stages to your process. Entrusting specialized processes – such as tissue management – to a skilled specialist ensures tissue uniformity while accelerating discovery.


Here’s just a sampling of what researchers have discovered using BrainBits® precision dissected live brain tissue, spinal cords, and DRGs.
  • A Potential therapeutic strategies for Alzheimer’s and Parkinson’s disease.
  • Bottleneck mitigation in the drug discovery process.
  • New and better alternative techniques for stimulation and recording of neural activity.
  • Improved understanding of how VGSC╬▓subunits regulate important cell processes.
  • New venues for developing neuroprotective and/or neurorestorative strategies against ischemic stroke.
  • Enhanced comprehension of the electrode/tissue interface in the spinal cord and dorsal root ganglion.
Discovery: It’s the end game. Whether your research investigates neurological disorders, examines biological mechanisms, or looks to further knowledge in the fields of neuroscience, pharmacology, or biotechnology, the quest for “aha” is every researcher’s Holy Grail.
Like so many worthwhile and challenging endeavours, in the race for discovery, protocols are precise and consistency is key. Meticulous tasks like harvesting neuronal tissue are vital to your research yet add unnecessary stages to your process. Entrusting specialized processes – such as tissue management – to a skilled specialist ensures tissue uniformity while accelerating discovery.

Product CodeProduct DescriptionPrice (£)
RhpcxvRat Combined Hippocampus, Cortex, and Ventricular Zone: 1 set195
RcxRat Cortex: 1 pair193
RhpRat Hippocampus: 1 pair193
RhtRat Hypothalamus: 1 pair193
RmbRat Midbrain: 1 Midbrain193
RscRat Spinal Cord: 1 Spinal Cord193
RstRat Striatum: 1 pair193
RwbRat Whole Brain: 1 brain195
RdrgRat Dorsal Root Ganglion (10 pairs per vial): 1 set396
MhpcxvMouse Combined Hippocampus, Cortex, and Ventricular Zone: 1 set195
McxMouse Cortex: 1 pair193
MhpMouse Hippocampus: 1 pair193
MhtMouse Hypothalamus: 1 pair193
MmbMouse Midbrain: 1 Midbrain193
MscMouse Spinal Cord: 1 Spinal Cord193
MstMouse Striatum: 1 pair193
MwbMouse Whole Brain: 1 brain195
MdrgMouse Dorsal Root Ganglion (10 pairs per vial): 1 set396
RPNcbRat Cerebellum: (minimum purchase of 2)218
RPNdrgRat Dorsal Root Ganglion (10 pairs per vial): (minimum purchase of 2)410
RPNwbRat Whole Brain: (minimum purchase of 2)218
Other ages/tissues from Postnatal rats and mice available upon requestEnquire
MPNcbMouse Cerebellum: (minimum purchase of 2)218
MPNdrgMouse Dorsal Root Ganglion (10 pairs per vial): (minimum purchase of 2)410
MPNwbMouse Whole Brain: (minimum purchase of 2)218
Other ages/tissues from Postnatal rats and mice available upon requestEnquire

Contact us today about BrainBits® and discover tomorrow.

www.caltagmedsystems.co.uk, email office@caltagmedsystems.co.uk or call +44 (0)1280 827460

Webmaster: AnnWebCom | Site design: custardcreative.co.ukCustard Creative Copyright 2005-2014 Caltag-Medsystems Limited - all rights reserved