Wednesday, 18 November 2015

Ubiquitin and Proteasome Research Reagents

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Adipogen - Distributed in the UK by Caltag Medsystems Ltd

       AdipoGen E-News | November 2015
Manufacturer of Quality Proteasome Research Reagents

Potent Proteasome Inhibitors

Salinosporamide A - UNIQUE                                                              AG-CN2-0444
Bortezomib [PS-341]                                                              AG-CR1-3602
Epoxomicin                                                        AG-CN2-0422
clasto-Lactacystin Beta-Lactone                                                              AG-CN2-0442
Lactacystin                                                                                                 AG-CN2-0104
Z-Leu-Leu-Phe-CHO [MG-110]                                                                                                 AG-CP3-0021
Z-Leu-Leu-Nva-CHO [MG-115]                                                                                                AG-CP3-0015
Z-Leu-Leu-Leu-CHO [MG-132]                                                                                                AG-CP3-0011
Z-Leu-Leu-Leu-B(OH)2 [MG-262]                                                                                             AG-CP3-0024
b-AP15 [DUB Inhibitor] Solution                                                                                             AG-CS1-0102

Proteasome Modulators

Betulinic acid [Proteasome Activator]                                                        AG-CN2-0415
Curcumin (high purity) [Proteasome Inhibitor]                                                           AG-CN2-0059
H(-)-Epigallocatechin gallate [Proteasome Inhibitor]                                                           AG-CN2-0063
Quercetin . dihydrate [Proteasome Inhibitor]                                                       AG-CN2-0409
Terrein [Proteasome Inhibitor]                                                             BVT-0193

Fluorescent Probes for Proteasome Activity Measurement

Ac-Arg-Leu-Arg-AMC                                                                                               AG-CP3-0013
Suc-Leu-Leu-Val-Tyr-AMC                                                                                                 AG-CP3-0016
Suc-Leu-Tyr-AMC                                                                                                              AG-CP3-0017
Z-Leu-Leu-Glu-AMC                                                                                                           AG-CP3-0022

Ubiquitin-Proteasome System Product Flyer


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T: +44(0)1280 827 460E: | W:

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Thursday, 22 October 2015

Peripheral Blood Mononuclear Cells from Solid Tumour Patients

                     Your Cell Culture Solutions   
         Peripheral Blood Mononuclear Cells
       from Solid Tumour Patients
            Our Cell Culture portfolio ranges from primary cells, stem cells,
        cell lines and media to skin, fresh animal brains, healthy &
            diseased products, angiogenesis models and transfection reagents.
          We’ve tried to make our product range as comprehensive as
           possible, but please let us know if you are having trouble sourcing
        a product or human/animal tissue and we will help you find it.
Contact us for more information.
                             +44 (0)1280 847460                                                            

Friday, 2 October 2015

Umbilical Cord Cell System

The umbilical cord cell system connects the developing embryo to the placenta. The umbilical cord arteries carry deoxygenated blood and waste from the embryo to placenta, while the umbilical cord vein supplies oxygenated and nutrient-rich blood to the fetus.
Endothelial cells and smooth muscle cells are essential components required for normal umbilical cord function. Abnormal cell proliferation and regulation within the umbilical cord system can contribute to the development of umbilical cord abnormalities.
We offer 4 types of normal human primary cells in the umbilical cord cell system including: umbilical vein endothelial cells, umbilical artery endothelial cells, umbilical vein smooth muscle cells, and umbilical artery smooth muscle cells.
Human Umbilical Vein Endothelial Cells                                                   - Each vial contains >5 x 10^5 cells in 1 ml volume.
- Guaranteed to further expand for 15 population doublings.  
- Recommended medium: Endothelial Cell Medium (Cat. #1001)

Immunostaining for Factor VIII, 200X.
Human Umbilical Artery Endothelial Cells
- Each vial contains >5 x 10^5 cells in 1ml volume.
- Guaranteed to further expand for 15 population doublings.
- Recommended medium: Endothelial Cell Medium (Cat. #1001)                         

Immunostaining for Factor VIII, 200x.
Human Umbilical Vein Smooth Muscle Cells
-Vascular SMC in culture play an important role in vascular disease research and can be used to identify new therapeutic targets to treat arterial disease.
- Each vial contains >5 x 10^5 cells in 1ml volume.
- Guaranteed to further expand for 15 population doublings.
- Recommended medium: Smooth Muscle Cell Medium (Cat. #1101)

Immunostaining for α-SMA, 400x.
Human Umbillical Artery Smooth Muscle Cells
- Vascular SMC in culture play an important role in vascular disease research and can be used to identify new therapeutic targets to treat arterial disease.
- Each vial contains >5 x 1^5 cells in 1 ml volume.
- Guaranteed to further expand for 15 population doublings.
- Recommended medium: Smooth Muscle Cell Medium (Cat. #1101)
Immunostaining for α-SMA, 200x.

2015 ScienCell Research Laboratories|6076 Corte Del Cedro, Carlsbad, CA 92011|(760) 602-8549
Caltag Medsystems is the UK distributor for ScienCell. For more information please contact:
T: +44(0)1280 827460 | F: +44(0)1280 827466 | E:

Monday, 14 September 2015

Visit us at the IBMS Congress!

Caltag Medsystems are pleased to be exhibiting at the Institute of Biomedical Sciences Congress on the 28-30th September at the International Conference Centre, Birmingham. 

The Biomedical Science Congress is three full days of active learning in science, education, training, management and leadership. It has grown to become the largest and most important meeting of its kind in the UK. For biomedical scientists at all levels, the IBMS Congress has proved to be a vital element of their scientific, professional and vocational development. 

If you are attending the Congress, come and visit us at Stand 320 to find out more about our wide range of products for the clinical environment. What's more, we are running a competition where you have the chance to win an Apple Watch!

Caltag Medsystems is ISO13485 accredited, supplying In Vitro Diagnostic products to clinical laboratories. Our portfolio includes the following products:

- Flow Cytometry reagents for Immune Monitoring and Immunophenotyping
- Screening tubes for Haematological Malignancies
- Blood/CSF Cellular Stabilisation Reagents
- Perinatal Diagnostic Reagents
- Diagnostic kits for disease areas including Autoimmunity, Oncology, Virology, Immunology   and Sepsis
- Automated Sample Preparation for Flow Cytometry
- Flow Cytometry Analysis Software

Caltag Medsystems will also be introducing The FlowStainer by Instrunor at the New Technology Showcase on the 28th between 12.00-12.30pm in Room B. If you would like to find out more, or to arrange a meeting with us during the congress please contact us at, or by calling us on 01280 827460.

Thursday, 3 September 2015

Back By Popular Demand: 20 for 20!

20ug of antibody for £20

No, you're not seeing things! We really are providing '20 for 20' on thousands of antibodies... Again!

If you're considering purchasing a new antibody and are looking for an economical way to test it, then look no further. We have 20ug sample sizes available for just £20.

View the full list of participating antibodies here (193kb). 

What's more, we're so confident that you'll like these antibodies, that we'll refund the £20 when you purchase a full size vial of any ProSci antibody!

So, how does it work? 

Choose any of the antibodies on the list and then place your order like normal with Caltag Medsystems. This offer is valid until the end of 2015. Maximum of 5 samples.

When we send your 20ug sample, we'll include a code for you to quote when ordering your full size vial of any ProSci antibody. That's 100ug or larger.

Let's get sampling... Again!

CaltagMedsystems are the exclusive UK and Ireland distributor for ProSci products. For further information about any of their other products, please call +44 (0)1280 827460 or email

Tuesday, 1 September 2015

Kappa & Lambda Antibodies – Multicolour Alternatives for Clonality Studies

Kappa and Lambda antibodies are widely used in routine diagnostics to evaluate a series of clinical conditions in which lymphoid populations are involved. Kappa/Lambda antibodies manufactured by Cytognos are the reagents of choice for EuroFlow™ antibody panels (FITC and PE), providing comparable results to polyclonal gold standards. These antibodies also show a high performance in extracellular and intracellular staining. Compared to other well-known Kappa/Lambda antibodies, Cytognos’ antibodies provide a superior mean fluorescence intensity and greater sensitivity. 

Products Available:

Product Description
Product Code

Single-Colour Antibodies

Double-Colour Combinations

Triple-Colour Combinations

Analysis of samples performed with Infinicyt - the unique software recommended by EuroFlow:

Cytognos’ Products are distributed exclusively in the UK by Caltag Medsystems. If you would like any further information on these products, please contact us by calling (+44) 01280 827460 or email

Caltag Medsytems provide a diverse range of flow cytometry products for diagnostic applications. 

Our Flow Cytometry portfolio includes an extensive number of controls for diagnostic purposes, such as CD4 Low and Normal Blood controls, fresh bone marrow, healthy & diseased cells and leukapheresis packs. We sell a number of Euroflow validated reagents, such as screening tubes for Leukaemia diagnostics and reagents for immunophenotyping. If you would like us to send you our Flow Cytometry brochure, please contact

Friday, 28 August 2015

Quantify Foetal Red Blood Cells: Introducing the FMH QuikQuant Assay

The enumeration of foetal red blood cells (fRBCs) is used to calculate the extent of Foetomaternal Haemmorhage (FMH), either in the case of trauma with suspected placental injury, or in the situation of RhD incompatibility between the foetus and the mother. The amount of fRBCs is a measure for the prevention of haemolytic disease of the newborn using prophylactic anti-D therapy.

The most widely used assay for FMH detection has been the visual microscopic counting Kleihauer Betke (KB) method, which is based upon differences in solubility properties in acid conditions of fetal hemoglobin (HbF) from adult hemoglobin. While the KB method is easily performed by most clinical laboratories, it lacks sensitivity and exhibits poor reproducibility or precision (CVs of 50-100%). 

The FMH QuikQuant assay uses an anti-Haemoglobin F monoclonal antibody and Propidium Iodide as a specific marker for nucleated cells. The whole assay takes less than one hour to complete, making it more efficient than the KB assay – as well as more sensitive and precise. Whilst the KB assay is performed by most clinical laboratories, the method exhibits poor reducibility or precision (CVs of 50-100%). Using FMH QuikQuant, samples with as low as 0.04% fRBCs can be significantly (P<0.05) distinguished from samples lacking foetal cells, as shown in the table below:

Table 1. Determination of assay sensitivity was performed by dilution studies of Trillium FETALtrol mixtures (high, low and negative levels) followed by replicate measurements on a Beckton Dickenson FACScan instrument.

Key Features:
- CE/IVD for FMH quantification
- Detection of HbF as low as 0.06% foetal cells in maternal blood
- Results within 1 hour with two single centrifuge steps

Product Information:
FMH QuikQuant (CE/IVD)
Product Code: QQF-100

Related Products:
FETALtrol (CE/IVD); A haematologic control for the detection of foetal red blood cells in maternal circulation.
- Available in 2 Sizes: 1 x 2ml and 2 x 2ml.

Caltag Medsystems are the exclusive UK and Ireland distributor for Trillium Diagnostics. For further information about the FMH QuikQuant or any of their products, please call +44 (0)1280 827460 or email

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