DNA Methylation Research Just Got Easier

DNA Methylation Research Just Got Easier

Accurately Measure Global 5-mC or 5-hmC in DNA in Just 2 Hours! Now you can save yourself the extra effort and quantify global 5-mC or 5-hmC levels in DNA in just one easy step with Epigentek’s MethylFlash™ Global DNA Methylation and Hydroxymethylation ELISA Easy Kits. These two new kits allow you to quantify global DNAmethylation or hydroxymethylation status by specifically measuring levels of 5-mC or 5-hmC in a simplified, "one-step" ELISA-like format.  Advantages & Features of MethylFlash Easy Kits: Fast - Reduced steps allow you to finish in only 2 hours Robust - Improved kits have a greater “signal window” with reduced variation between replicates Convenient - Inherently low background noise without the need for DNA denaturation and plate blocking steps Sensitive - Detection limit can be as low as 0.05% methylated or 0.01% hydroxymethylated DNA from 100 ng of input DNA Specific - No cross-reactivity to unmethylated or other modified cytosines Universal - Included positive and negative controls allow for detection of DNA methylation or hydroxymethylation in any species from either single-stranded or double-stranded input DNA Accurate - Optimized positive controls that can be fractionalized in percentage scale, allowing the assays to be more accurate and highly comparable with HPLC-MS analysis Flexible - Strip-well microplate format for manual or high throughput analysis Plus, save 25% for a limited time!  View DNA Methylation Kits DNA Hydroxymethylation Kits How are these new kits different from the previous MethylFlash kits? The MethylFlash Easy kits, while still retaining the many advantageous features of the previous kits, utilises a “one-step” ELISA reaction to eliminate the need for multiple sample and antibody binding steps. The protocols of these new kits are simplified, reducing the procedure times by 50% versus the previous MethylFlash kits. Some adjustments were made to also reduce the CV% between wells. The greater “signal window” of each kit, along with adjusted calculation formulas, makes these new kits very accurate. In a nutshell, MethylFlash Easy kits are faster, easier, more robust, and more accurate. Find Out More Epigentek products are distributed in the UK by Caltag Medsystems Ltd.