Wednesday, 27 June 2012

NAMPT [VISFATIN/PBEF] – Linking NAD Biology, Metabolism and Cancer

Nicotinamide phosphoribosyltransferase (Nampt; pre-B cell colony-enhancing factor; PBEF; Visfatin) is an 52kDA adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form (eNampt). While the function of iNampt as an essential and rate-limiting NAD+ biosynthetic enzyme is well established, the physiological role of eNampt is still a matter of debate. It has been shown that Nampt expression is increased in different diseases, like diabetes, obesity, fetal growth retardation, sepsis, inflammatory bowel disease, Crohn’s disease and rheumatoid arthritis. Furthermore, Nampt might be a marker of pre-eclampsia and of endothelial health.

For product references, please view this page.

Nampt (Visfatin/PBEF) (human) ELISA Kit
- Product Code: AG-45A-0006EK-KI01 (1 x 96 well)
- Product Code: AG-45A-0006PP-KI01 (5 x 96 wells)
- Product Code: AG-45A-0006TP-KI01 (2 x 96 wells)
Download the product datasheet here.


Also available…

Nampt (Visfatin/PBEF) (human) (IntraCellular) ELISA Kit
- Product Code: AG-45A-0008
Download the product datasheet here.

Nampt (Visfatin/PBEF) (mouse/rat) Dual ELISA Kit
- Product Code: AG-45A-0007
Download the product datasheet here.

Nampt (Visfatin/PBEF) (mouse/rat) (IntraCellular) Dual ELISA Kit
- Product Code: AG-45A-0009
Download the product datasheet here.

1 comment:

  1. Hello, I just wanted to say that I really enjoyed your site and this post. You make some very informative points.Keep up the great work!

    NAD Assay Kit

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