Tuesday, 29 May 2012

ELISA Kit for Gelsolin (GS)


Gelsolin is an actin-regulatory protein that modulates actin assembly and disassembly, and is believed to regulate cell motility in vivo through modulation of the actin network. In addition to its actin-regulatory function, gelsolin has also been proposed to affect cell growth.It is first isolated from rabbit lung macrophages as a modulator of the cytoplasmic actin gel−sol transformation. Gelsolin can sever actin filaments and cap the fast-growing ends of the filaments in vitro; this promotes actin disassembly. Gelsolin also has the ability to nucleate actin polymerization. These functions are activated by Ca2 and inhibited by polyphosphoinositides (PPIs). Such observations have led to the view that gelsolin regulates actin reorganization in response to changes in the concentrations of Ca2 and PPIs in living cells.

Product Code: E90372Hu
Download product datasheet here.

ELISA Kit for Gelsolin is also available in Mouse, Rat and Monkey. Please contact us if you are interested in these products.

We offer the lowest prices on Uscn ELISAs – and Bulk Discounts! Click here for more information. 

Caltag Medsystems is the UK distributor for Uscn and they currently have over 4,600 ELISA Kits in their portfolio. Search the complete Uscn product range by product type and/or species reactivity in excel format here.

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