Thursday, 16 February 2012

VASPIN – Potential Biomarker for Obesity

Vaspin (Visceral adipose tissue-derived serpin; Serpin A12), a serine protease inhibitor (serpin), is an insulin-sensitizing adipocytokine that has been isolated from both visceral and subcutaneous white adipose tissue. Based on recent findings, vaspin is suggested to regulate immune responses and inflammation and was found to be correlated with various metabolic parameters.

Human vaspin blood levels are significantly increased in type 2 diabetes mellitus and obese patients. Thus vaspin may represent a novel biomarker for obesity and impaired insulin sensitivity and might serve as a new therapeutic target of metabolic syndrome.

Vaspin (human) ELISA Kit

Sensitivity: 12 pg/ml
Range: 0.016 to 1 ng/ml
Sample type: Serum, plasma, cell culture supernatant

Product Code: AG-45A-0017EK-KI01 (1 x 96 well plate)
Product Code: AG-45A-0017TP-KI01 (2 x 96 well plate)
Product Code: AG-45A-0017PP-KI01 (5 x 96 well plate)

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