- Useful for transporter related diseases and drug discovery
- Solute carrier antibodies have been verified by analysis of cells transfected with full length SLC cDNA
- Applications: FCM, WB, ICC, IHC
Monday, 13 August 2012
Solute Carriers from MBL International
Many
important nutrients, including glucose and amino acids, are water soluble.
Transporter proteins enable water soluble nutrients to cross the lipid double
membrane and enter the cell. These membrane transporters form a large and
diverse family of proteins which are highly selective for specific solutes,
called solute carriers (SLC). Transporters can be divided into pumps (ATP
binding cassette) which consume energy by hydrolyzing ATP, and carriers which
facilitate the diffusion of solutes without use of ATP. The human genome encodes
49 known pumps and 360 solute carrier proteins. Transporters are expressed
throughout the body, but are most abundant in kidney, liver and the nervous
system.
Featured product:
To view MBL’s product range of solute
carriers click here.
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