Monday, 11 June 2012

ELISA Kit for Interleukin 35 (IL-35)

Interleukin 35 (IL-35) is an IL-12 family cytokine that is produced by regulatory, but not effector, T cells and plays a role in immune suppression. It is a dimeric protein composed of IL-12α and IL-27β chains, which are encoded by two separate genes called IL12A and EBI3, respectively.

- Product code: E92008Hu

Secreted by regulatory T cells (Tregs), IL-35 suppresses inflammatory responses of immune cells. Studies in mice show the absence of either IL-35 chain from regulatory Tregs reduces the cells ability to suppress inflammation; this has been observed during cell culture experiments and using an experimental model for inflammatory bowel disease. To produce its suppressive effects, IL-35 has selective activities on different T cell subsets; it induces proliferation of Treg cell populations but reduces activity of Th17 cell populations.
Download the product datasheet here.

ELISA Kit for Interleukin 35 (IL-35) is also available in Mouse. Please contact us if you are interested in this product.

We offer the lowest prices on Uscn ELISAs – and Bulk Discounts! Click here for more information.

Caltag Medsystems is the UK distributor for Uscn and they currently have over 4,600 ELISA Kits in their portfolio. Search the complete Uscn product range by product type and/or species reactivity in excel format here.

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