Tuesday, 1 May 2012

Anti-PIP3 [phosphatidyl inositol-3,4,5-triphosphate] Monoclonal Antibody

PIP3 plays multiple roles in regulating cell growth and survival.  Approximately 50% of all cancers possess mutations in genes that regulate PIP3 production, resulting in cells with abnormally high levels of PIP3. PIP3 acts as a critical second messenger in insulin signalling; and is also involved in T cell activation via CD28, regulating exocytosis, and inducing actin reorganization and membrane ruffling.

Recent Citation: Melkam Kebede, et. Al., PNAS, Feb 2012; 109: 2376 - 2381 
Anti-PIP3 [phosphatidyl inositol-3,4,5-triphosphate] Monoclonal Antibody, 100ul

Product Code: D145-3

Download datasheet here

Caltag Medsystems is the exclusive UK distributor for MBL products. For further information on the MBL product range, please visit http://www.mblintl.com or request a copy of the MBL reference guide.


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