Friday, 20 April 2012

ELISA Kit for Hepcidin (Hepc)


Hepcidin is a peptide hormone produced by the liver discovered in 2000, that appears to be the master regulator of iron homeostasis in humans and other mammals. In humans, HAMP is the gene that encodes for hepcidin. 

- Product code: E91979Mu
- Product code: E91979Hu
- Product code: E91979Ra
- Product code: E91979Po
- Product code: E91979Bo

Hepcidin preprohormone, prohormone and hormone size are 84, 60 and 25 amino acids respectively. 20 and 22 amino acid forms of Hepcidin also exist in the urine. The N terminal region is required for function, and deletion of 5 N-terminal peptides results in a loss of function. Hepcidin has a beta-sheet rich structure with 4 disulfide bonds. Hepcidin directly inhibits ferroportin, a protein that transports iron out of cells that store it. This prevents enterocytes of the intestines from secreting iron into the hepatic portal system, reducing iron absorption.

We offer the lowest prices on Uscn ELISAs – and Bulk Discounts! Click here for more information
Caltag Medsystems is the UK distributor for Uscn and they currently have over 4,600 ELISA Kits in their portfolio. Search the complete Uscn product range by product type and/or species reactivity in excel format here.

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