Friday, 2 December 2011

Epigenetic ELISA Kits from Abnova


The field of epigenetic screening has become one of the most exciting areas of biological research and is increasingly becoming the focus of drug developments. Epigenetic mechanisms are inheritable factors that regulate genetic expression without changing the DNA sequence.

Factors such as post translational modifications on the N-terminal tails of histones or methylation on the cytosine of DNA can induce changes to chromatin structure, thereby regulating DNA expression. Abnormalities in this process play a critical role in many important human diseases, especially in cancer and metabolic diseases. Abnova provide robust and ready-to-use assay kits with specific antibodies and innovative detection methods that can shorten assay times.

Abnova Epigenetic Kit Categories:

DNA Methylation (10 Kits): Methyltransferase Assay, Demethylase Assay, Quantification, Capture
Histone Methylation (54 Kits): Methyltransferase Assay, Demethylase Assay, Quantification
Histone Acetylation (21 Kits): Acetyltransferase Assay, Deacetylase Assay, Quantification
Histone Phosphorylation (5 Kits): Quantification

Advantages of these Products:
  • Quick and efficient
  • Innovative colorimetric and fluorometric assays
  • Very sensitive, requiring very low amounts
  • Controls are conveniently included for quantification
  • Strip microplate format makes the assay flexible: manual or high throughput
  • Simple, reliable, and consistent assay conditions
  • In situ histone phosphorylation and methylation kits available (whole cell-based detection)
Note - These advantages apply to the majority of our kits. Please refer to product protocols for specific details.

Epigenetic Antibody Showcase:

Epigenetics Antibodies. 3541 antibodies for the study of heritable changes in gene function without DNA sequence change
Chromatin Regulation Antibodies. 1127 antibodies for histone, histone demethylases and chromatin structure modification
Histone Deacetylase Antibodies. 144 antibodies against enzymes that remove acetyl groups from histones
DNMT Antibodies. 20+ antibodies for DNA methyltransferase family to transfer a methyl group to DNA
ChIP Antibodies. 91 specific antibodies for Chromatin Immuno-precipitation, CIITA, ESR1, H3F3A, HDAC1, and more.

Caltag Medsystems is the UK distributor for Abnova, please visit www.caltagmedsystems.co.uk or call 01280827460 for UK pricing.

1 comment:

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