Tuesday, 8 November 2011

TransFix® from Cytomark

TransFix® is a preservative solution that maintains cellular integrity while at the same time preserving antigenicity. It can be used to preserve and stabilise body fluids including blood, CSF, bone marrow and fine needle aspirates. TransFix® treated samples are stable for up to 10 days when stored at 40C. TransFix® has been used extensively in the immune monitoring of HIV patients and in immunophenotyping. The launch of 3ml and 10ml vacuum blood collection tubes containing TransFix/EDTA has led to extensive use by clinical research organisations in support of international clinical trials.

Orfao et al (2009) researched the diagnosis of Leptomeningeal Disease and found that in up to 40% of samples cell lysis occurs before the sample can be tested . When stabilised with TransFix® all cell bearing samples can be diagnosed. This led to the conclusion that failure to use a preservative could result in 30% of adverse pathologies not being reported due to cell lysis.

Free samples are available for validation testing – please email office@caltagmedsystems.co.uk for more information. For more information, publications and resources check out our website.

Orfao, A. et al (2009) ‘Identification of Leptomeningeal Disease in Aggressive B-Cell Non-Hodgkin's Lymphoma: Improved Sensitivity of Flow Cytometry’, Journal of Clinical Oncology, vol. 27, no. 9, 1462-1469

No comments:

Post a Comment

Webmaster: AnnWebCom | Site design: custardcreative.co.ukCustard Creative Copyright 2005-2015 Caltag-Medsystems Limited - all rights reserved