Wednesday, 10 August 2011

Monosan launch new antibody

Mouse anti-Cytokeratin 5⁄6 with clone D5/16B4.

This antibody, with product code MON9125, reacts with Cytokeratin 5/6 and reacts weakly with Cytokeratin 4. Cytokeratin 5/6 are known as high molecular weights cytokeratins, and are part of the basic subfamily of cytokeratins. These two cytokeratins are closely related and are focused in non-keratizing stratified squamous epithelia, apocrine and sweat glands of skin, epidermis, hair follicles and mammalian glands.

MON9125 stains the basal cells of squamous and glandular epithelia, part of stratum spinosum of squamous epithelium, myoepithelium, and mesothelium. It does not stain adenous epithelium. Therefore, this antibody can be used to distinguish squamous carcinoma from adenocarcinoma and to differentiate epitheloid mesothelioma from non-epitheliod mesothelioma and adenocarcinoma. It is also a useful antibody to distinguish benign ductal hyperplasias from non-invasive neoplastic proliferations.

Product Code: MON9125

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