Monday, 15 August 2011

AdipoGen ELISA kits...

AdipoGen have a wide range of ELISA kits including:
Progranulin – A new ligland to TNF receptors
Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signalling cascades that control cell cycle progression and cell motility. Progranulin mutations are connected to Alzheimer’s disease (AD). Progranulin detection is a potential biomarker for AD and Mild Cognitive Impairment (MCI). Progranulin binds to TNF receptors and is therapeutic against inflammatory arthritis in mice.

The AdipoGen ELISA comes in 3 sizes; 1 x 96 well plate, 2 x 96 well plates, 5 x 96 well plates.

  • For a quantitative and specific measurement of BAFF levels

  • The first “highly sensitive” mAb/mAb-based human BAFF immunoassay

  • Detects BAFF levels in patients with healthy and pathological conditions

  • Secured re-supply – available from stock

  • Inter- and intra- batch reproducibility

  • Small original sample amounts – only 5ul needed

  • Works on serum, plasma and cell culture supernatant
BAFF ELISA kit comes in one size; 1 x 96 well plate.

Sirtuin 1 (Intracellular) ELISA kit

Sirtuins (Silent information regulators; SIRTs) deacetylate and/or ADP-ribosylate lysine residues of target proteins in an NAD+-dependent manner. Sirtuins are critical regulators of many cellular processes, including insulin secretion, the cell cycle and apoptosis. Sirtuins, in particular SIRT1, emerged as critical regulators of longevity and aging in several model organisms. Furthermore, a variety of age-associated diseases such as type 2 diabetes, obesity, osteoporosis, and Alzheimer’s disease are associated with sirtuins. SIRT1 has been suggested as potential biomarker for tumorigenesis.

This Adipogen ELISA comes in 2 pack sizes: 1 x 96 well plate and 2 x 96 well plates.

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