Monday, 25 July 2011

Signosis - Human p450 cDNA Plate Array


Cytochrome P450 is a multi-gene family of enzymes, which play a central role in the oxidative metabolism of a wide range of xenobiotics, including anticancer drugs. Human CYP genes encode fifty-seven P450 proteins with numerous homologue variants in different tissues. They are highly differentially expressed in response to a variety of environmental chemicals and pharmaceuticals.

Signosis have developed a P450 cDNA Plate Array for profiling the expression of a panel of 22 of these CYP genes.

Human p450 cDNA Plate Array, Product code: AP-0202

Analysis of expression of P450 genes. 2ug of RNAs from MCF7, HL-60, HeLa and 293 cell lines were subjected to the P450 cDNA plate assay.

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