Friday, 29 July 2011

MBL RIP-Chip Assay for microRNA


MBL was established in Japan and originally concentrated on the development and production of immunological diagnostic reagents, especially for collagen diseases and autoimmune diseases.
In 1993 MBL International was established in the USA and is now a leading life science company focused on providing high quality products and solutions for life science research and clinical diagnostics. Much of the focus is in the areas of Apoptosis, Signal Transduction, Cell Proliferation and Heat Shock Proteins, as well as many other areas of cell biology.

RIP-Chip Assay:
RNA-Binding Protein Immunoprecipitation – RIP-Chip – is a technology used to identify functionally related mRNAs and other RNAs associated with RNA binding proteins (RBP).
RBPs are significant factors that regulate and coordinate gene expression of multiple mRNAs and noncoding regulatory RNAs.
See below for MBL’s educational video on RIP-Chip assay microRNA.
  • Identify miRNAs bound to their mRNA targets
  • Analyse the maturation mechanism of miRNA
  • Identify novel miRNA and construct miRNA libraries

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